Heart lessons

Heart lessons

Braz J Cardiovasc Surg | Rev Bras Cir Cardiovasc he last 12 months have been of deep losses for the Brazilian cardiovascular surgery. Distinguished and competent professionals, fundamental to the consolidation and advancement of the specialty in our country have left us, after serving brilliantly their career in this world. On July 10, 2014, Dr. Geraldo Verginelli died. On November 12, 2014, Dr...

Cell Junctions: Lessons from a Broken Heart

In a case of the familiar being strange, new work shows that the integrity of the Drosophila cardiac system depends on septate-junction proteins even though the heart lacks discernable septate junctions.

Perhexiline: lessons for heart failure therapeutics.

SEE PAGE 202 I n heart failure with reduced ejection fraction, mechanical work produced by the left ventricle to support the systemic circulation decreases over time despite relatively constant myocardial oxygen consumption. The resulting decrease in the ratio of mechanical work to oxygen consumed, or mechanical efficiency, is a cardinal feature of heart failure (1). Extensive research in exper...

Lessons from the European heart survey.

Electrophysiological Mechanisms of Gastrointestinal Arrhythmogenesis: Lessons from the Heart

Disruptions in the orderly activation and recovery of electrical excitation traveling through the heart and the gastrointestinal (GI) tract can lead to arrhythmogenesis. For example, cardiac arrhythmias predispose to thromboembolic events resulting in cerebrovascular accidents and myocardial infarction, and to sudden cardiac death. By contrast, arrhythmias in the GI tract are usually not life-t...